Dog allergies are unfortunately very common. In fact, allergies are the most common reason for veterinary appointments. Allergies with symptoms ranging from mild itching to severe skin issues and even gastrointestinal issues are known as Pruritus.
While humans and dogs get skin allergy symptoms, dog allergies affect both the skin and ears. Unlike humans, whose skin allergies often diminish with age, dog allergies can worsen over time, according to experienced veterinarians.
Dog allergies can occur for many reasons. For example, flea bites, even as few as 1 flea bite a week is enough to cause skin allergies in some dogs. Allergy to dog food is another cause of canine allergy. Just as highly processed foods for humans is now recognized by leading nutrition science as bad for your health, so too is the highly processed dog food known as kibble. Unless you are feeding your dog fresh or frozen raw dog food, you, and the majority of pet parents, are probably feeding your dog kibble.
Many pet owners are increasingly concerned about the health implications of feeding their dogs commercially processed kibble, particularly because those are generally manufactured under high heat and pressure conditions that can create potentially harmful chemical byproducts. Dog food manufacturers will commonly add back some nutritional vitamins that are lost to the heat of processing. While most commercial dog foods undergo extreme heating that can generate toxic compounds, specialized independent companies making food toppers containing targeted anti-inflammatory and anti-oxidant ingredients may address these processing-related health risks. Understanding how these dangerous high heat processed compounds form we asked practicing veterinarians about how therapeutic toppers for dog allergies can mitigate their effects is important for maintaining your dog’s long-term health.
Common Allergens in Dog Food
About 95% of dry pet foods are processed using extremely high temperatures between 300°F to 400°F (150°C to 200°C), for extended processing times under high pressure in specialized extrusion machines (Darin Machinery 2024). In addition to traditional food allergens, the intensive thermal processing also produces inflammatory triggers and potential carcinogens that can trigger allergic and inflammatory responses in dogs.
Acrylamide can be formed in high-carbohydrate foods during extrusion and other high temperature process like roasting, frying and baking (Jackson & Al-Taher 2005). Research shows that high acrylamide levels have been found in dry dog food like kibble. Side effects of long-term exposure of acrylamide include problems like cancer development… the more processing the higher the acrylamide levels (Jackson & Al-Taher 2005).
Other high-heat pet food by-products linked to aging and disease include advanced glycation end products (AGEs) shown to trigger inflammatory diseases such as arthritis, diabetes mellitus and other diseases according to scientifically backed research (Bark & Whiskers 2017). Extrusion produces heterocyclic aromatic amines from cooking meat, poultry, and fish known to produce various tumors in rats (PMC3534781 2012).
In addition to process-induced chemicals, traditional food allergens can be a problem for some dogs. In dogs with food allergies, among the causes of allergic reaction are beef, dairy, chicken, wheat and lamb. Science shows that combining natural food allergies with the toxins in highly processed dog food only makes matters worse. Your veterinarian is the best resource for addressing severe dog food reactions your dog may display.
Benefits of Limited-Ingredient Toppers
Limited ingredient veterinarian approved dog food toppers can provide advantages for dogs exposed to the toxic byproducts of various kibbles. Limited ingredient topper makes it easier for pet parents to identify what their dogs are eating. Your veterinarian will agree that a science-based topper that’s tasty is appealing to picky eaters.
Specialized toppers can counteract the inflammatory damage caused by process-induced toxins. Research shows that toppers with anti-inflammatory properties can help reduce redness and itching generally associated with seasonal allergies if they can provide anti-oxidant and anti-inflammatory properties that promote a more balanced immune system response, itch relief and a healthy skin. Research indicates that a topper with mitochondrial wellness properties is an added benefit.
While elimination diets act to avoid potential allergens, anti-inflammatory toppers are active in neutralizing oxidative stress and inflammation caused by highly processed dog foods which have increased markers of liver stress and inflammation compared to those on raw or minimally processed diets (Albright’s Raw Dog Food 2025).
How Quelle365 Addresses Allergy Concerns
Quelle365 Daily Vitality Dog Food Topper For Allergies can answer the question “Dog Food Toppers for Allergies: Do They Work?” Quelle365 is a pharmacist formulated and veterinarian approved supplement addressing both traditional allergies and inflammatory damage caused by kibble processing toxins. Its patented eCSEPTIONOL® Formula base contains five science backed natural ingredients carefully chosen for their ability to combat the chronic systemic inflammation, including inflammation resolution support. Veterinarian approved Quelle365 ingredients are uniquely protective of mitochondrial wellness that means additional anti-inflammatory protection for your pooch include:
PEA (Palmitoylethanolamide) – Master Inflammatory Mediator:
PEA is scientifically shown to down-modulates allergic hyperactivity, decreasing mediator release from mast cells (PMC9496254 2022). In clinical dog studies, PEA significantly reduced itching of pruritus in study dogs with atopic dermatitis, while 58% showing greater than 2 cm reduction in itch scores and 30% achieving absent-to-very-mild- pruritus (PMC8065429 2021). PEA counteracts itch inflammation and discomfort making it very valuable for dogs with moderate atopic dermatitis while protecting against the inflammatory cascade triggered by high-processed toxins (CanineCeuticals 2024).
BCP (Beta-Caryophyllene) – Targeted CB2 Receptor Activation: This natural cannabinoid interacts with the endocannabinoid system CB2 receptors primarily regulating immune function, inflammation and pain perception and properties to help reduce inflammation in joints and throughout the body according to university veterinary school reserach (Cannanda 2025).
DHA (Docosahexaenoic Acid) – Specialized Inflammation Resolution: An abundance of clinical research shows that DHA supplementation has proven benefits in the adjunct treatment (i.e., that are approved for use with medically approved Standard of Care drugs) of canine allergic dermatitis and DHA-rich supplements can calm itchy or dry skin and other adverse side effects that result from allergic reactions (Veterinary Formula 2025).
ASX (Astaxanthin) – Cellular Protection and Immune Enhancement: Dietary ASX offers enhanced immune responses and reduced inflammation in dogs. ASX supplementation reduced markers of oxidative stress and inflammation (Pet Longevity Project 2024). Dogs eating processed kibble benefit from its anti-inflammatory effects throughout the body, potentially alleviating veterinarian reported symptoms of arthritis, allergies, and autoimmune diseases (Pet Longevity Project 2024).
QUE (Quercetin) – Nature’s Antihistamine: Widely recognized as “nature’s Benadryl” this natural antihistamine, anti-inflammatory and anti-oxidant, can turn off histamine production and control inflammation (Bonza 2025). QUE’s anti-histamine properties can reduce sneezing, itching and other allergic reactions by suppressing histamine by blocking mast cell release of histamine and inhibiting other inflammation enzymes in clinical tests (Native Pet 2023).
Synergistic Protection Against Processing Toxins:
The combination of these five ingredients in Quelle365 dog food topper for allergies creates a comprehensive defense against both traditional allergens and the toxic process compounds. This vet approved multi-target approach to chronic systemic inflammation (CSI) mechanisms help neutralize the oxidative stress, cellular damage and inflammatory cascade caused by long-term exposure to processing-induced toxins based on scientific research.
Introducing New Toppers Safely
When introducing any veterinarian approved specialized topper like Quelle365 to counteract the effects of processed kibble, an introduction protocol is essential for optimal results and safety when answering the question “Dog Food Toppers for Allergies: Do They Work?”.
Begin with a minimal dose: If you are unsure, check with your veterinarian first before starting any new diet. If you decide on Quelle365, begin with a with a normal serving on the first day to give your dog’s system a chance to react to something new. If no changes in your dogs behavior or digestion process, then it should be ok to continue to sprinkle Quelle365 dog food topper powder for allergies onto their regular food at the same meal once a day to establish consistency. This enables the pharmacist formulated anti-inflammatory ingredients to begin working on the cellular level where it can begin to promote mitochondria wellness in addition to its anti-inflammatory and anti-oxidant properties even as it allows your dog’s system to adapt.
Soon, look for positive changes that can take up to a few weeks until the body adjusts. Just as prescription drugs require larger doses if your dog is very large and weighs more than 60 pounds, it may require a double dose of topper.
When to Talk to Your Vet About Allergies
Consulting your veterinarian is always a good idea when dealing with allergies of any kind especially when addressing allergies in dogs eating highly processed kibble as their main diet. The combination of traditional allergens and processing-induced toxins creates complex inflammatory patterns may require professional assessment. After proper medical assessment by your veterinarian it may be advised to change your dogs primary diet to raw fresh dogfood in addition to Quelle365 dog food topper for allergies. Always check with your veterinarian whenever your dog is experiencing serious symptoms of pruriuts. QuelleDVM, a higher strength anti-inflammatory topper available through participating veterinarians is approved as adjunct therapy for prescription products like Apoquel®.
Long-term health monitoring is advised for dogs on kibble diets, due to exposure to acrylamide, AGe’s and heterocyclic amines, that can have cumulative health effects. The integration of specialized toppers like Quelle365 should always be discussed with your veterinary team to ensure they complement your dog’s overall allergy management plan while providing ongoing protection against processing-induced inflammatory damage. We hope this article has been able to provide a professional response to your questions about ‘Do Dog Food Toppers for Allergies Work?’
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